Approach to the synthesis of antitumor quassinoids from labdane diterpenes: an efficient synthesis of a picrasane-related intermediate.
نویسندگان
چکیده
[structure: see text]. The tetracyclic ketal 24, a suitable intermediate for the synthesis of antitumor pentacyclic quassinoids, has been efficiently prepared from communic acids (5a-c), via methyl ketone 9. The synthetic sequence from 9 to 24 consists of 15 steps in 12% overall yield.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 3 5 شماره
صفحات -
تاریخ انتشار 2001